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Pharmacokinetic interactions between phenylpropanolamine, caffeine and chlorpheniramine in rats

โœ Scribed by Amal Kaddoumi; Mihoko N Nakashima; Mitsuhiro Wada; Kenichiro Nakashima

Book ID
113591328
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
127 KB
Volume
22
Category
Article
ISSN
0928-0987

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โœ Hirokazu Yamaji; Yasuhiro Matsumura; Yukako Yoshikawa; Kanji Takada ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 171 KB ๐Ÿ‘ 2 views

The interactions of four HIV-protease inhibitors, ritonavir (RIT), saquinavir (SAQ), indinavir (IND) and nelfinavir (NEL), were examined by in vitro metabolic studies using rat liver microsomal fractions. The substrate concentrations employed were 0.75 12 mM, and the inhibitor concentrations were 2.