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Pharmacokinetic evidence for the occurrence of extrahepatic conjugative metabolism of p-nitrophenol in rats

✍ Scribed by Minoru Machida; Yoko Morita; Masahiro Hayashi; Shoji Awazu

Book ID
115776415
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
615 KB
Volume
31
Category
Article
ISSN
0006-2952

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The objective of this study was to characterize the extent of the formation of the active (trans-alcohol form) and inactive (cis-alcohol) metabolites of loxoprofen and to compare the kinetics after its intragastric, intravenous, and intramuscular administrations in rats. After intravenous administra