Loratadine administered concomitantly wi
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Brannan, Melvin D.; Reidenberg, Pascale; Radwanski, Elaine; Shneyer, Lucy; Lin,
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Article
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1995
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Nature Publishing Group
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English
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assessment of potential adverse drug interactions resulting from hepatic cytochrome P450 isozyme inhibition can be evaluated by studying the effects of concomitant administration of one drug with another drug that inhibits specific isozymes. Cytochrome P4503A4 (CYP3A4) is involved in the metabolism