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Pharmacokinetic aspects of the interaction between clobazam and cimetidine

✍ Scribed by H. -G. Grigoleit; P. Hajdú; H. K. L. Hundt; D. Koeppen; V. Malerczyk; B. H. Meyer; F. O. Müller; P. U. Witte

Publisher
Springer
Year
1983
Tongue
English
Weight
374 KB
Volume
25
Category
Article
ISSN
0031-6970

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Four normal volunteers each received three intraduodenal infusions of 0.5 mg triazolam solutions. Three treatments were: 1. a pH 2.3 solution in which 47 per cent of the dose had hydrolysed to form a triazolo-benzophenone (TB); 2. a pH 6.0 solution containing negligible TB; 3. the p H 6.0 solution