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Pharmacokinetic and Pharmacodynamic Properties of Buprenorphine After a Single Intravenous Administration in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

✍ Scribed by Monica Escher; Youssef Daali; Jocelyne Chabert; Gérard Hopfgartner; Pierre Dayer; Jules Desmeules


Book ID
116372029
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
895 KB
Volume
29
Category
Article
ISSN
0149-2918

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## Background Interferon (IFN) alpha conjugation to polyethylene glycol (PEG) results in a better pharmacokinetic profile and efficacy. The aim of this study was to compare the pharmacokinetic, pharmacodynamic and safety properties of a new, locally developed, 40-kDa PEG-IFN alpha-2b preparation wi