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Pharmacokinetic and pharmacodynamic modelling of trimazosin and its major metabolite

โœ Scribed by Peter A. Meredith; Andrew W. Kelman; Henry L. Elliott; John L. Reid

Book ID
112472245
Publisher
Springer
Year
1983
Tongue
English
Weight
577 KB
Volume
11
Category
Article
ISSN
1573-8744

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Modeling the pharmacokinetics and pharmacodynamics of trimazosin
โœ A. W. Kelman; P. A. Meredith; H. L. Elliott; J. L. Reid ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 585 KB

The pharmacokinetics and pharmacodynamics of trimazosin are described following both intravenous and oral administration to 6 normotensive, male volunteers. The IV and oral drug and metabolite (l-hydroxytrimazosin) concentration data are fitted simultaneously to the same pharmacokinetic model. The p