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Pharmacokinetic and local toxicity studies of liposome-encapsulated and plain mepivacaine solutions in rats

✍ Scribed by Tofoli, Giovana Radomille; Saia Cereda, Cíntia Maria; de Araujo, Daniele Ribeiro; Paula, Eneida de; Brito Júnior, Rui Barbosa; Júnior, José Pedrazzoli; Meurer, Eduardo; Proença Barros, Fábio Alessandro; Groppo, Francisco Carlos; Volpato, Maria Cristina; Ranali, José

Book ID
120327831
Publisher
Informa plc
Year
2010
Tongue
English
Weight
802 KB
Volume
17
Category
Article
ISSN
1071-7544

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PHARMACOKINETIC EVALUATION OF LIPOSOMAL
PHARMACOKINETIC EVALUATION OF LIPOSOMAL ENCAPSULATED AMPICILLIN IN MALE AND FEMALE RATS
✍ ROSELINE L. PARDUE; CATHERINE A. WHITE 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 179 KB 👁 2 views

The dispositions of free and liposomal entrapped ampicillin were compared in male and female rats after IV administration. Serial blood samples were collected for 2 h in the free drug study and 12 h for the liposomal formulation. Pharmacokinetic parameters obtained with free drug were not signi®cant