Pharmacokinetic and bioequivalence evaluation of two generic formulations of oral artesunate
โ Scribed by K. Na-Bangchang; J. Karbwang; K. Congpoung; A. Thanavibul; R. Ubalee
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 252 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0031-6970
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Two oral pharmaceutical formulations (URO-TS D" and Bactrim F") containing 800 mg of sulfamethoxazole (SMZ) and 160 mg of trimethoprim (TMP) were given to 10 Mexican healthy volunteers, following a randomized cross-over design. Blood and urine samples were obtained, concentrations of TMP, SMZ, and i
## Purpose: The purpose of this randomized, crossover study was to compare the bioavailability of a generic and an innovator formulation of nizatidine 300 mg capsules under fasting conditions. ## Methods: Twenty blood samples per period were collected from 20 healthy, arab male volunteers over 16