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Pharmacokinetic Analysis of the Absorption Characteristics of Diclofenac Sodium in Man by use of a Multi-segment Absorption Model

✍ Scribed by Iftekhar Mahmood


Book ID
118110112
Publisher
Pharmaceutical Press
Year
1996
Tongue
English
Weight
307 KB
Volume
48
Category
Article
ISSN
2042-7158

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The pharmacokinetics of pafenolol, a highly selective /?,-adrenoceptor antagonist, have been studied in starved and unstarved rats. Separate groups received intravenous doses (0.3 and 3.0pmol kg-I) and oral doses (1 and 25pmol kg-I). The systemic clearance of pafenolol was constant in the dose range