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Pharmacokinetic Analysis of Free Radicals by in vivo BCM (Blood Circulation Monitoring)-ESR Method

✍ Scribed by Takechi, Koji; Tamura, Hideyuki; Yamaoka, Kiyoshi; Sakurat, Hiromu

Book ID
126616926
Publisher
Informa plc
Year
1997
Tongue
English
Weight
824 KB
Volume
26
Category
Article
ISSN
1071-5762

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Competition of nitroxyl contrast agents
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✍ Aya Okajo; Ken-ichiro Matsumoto; James B. Mitchell; Murali C. Krishna; Kazutoyo πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 592 KB

## Abstract Nitroxyl radicals used as tissue redox‐sensitive contrast agents in electron paramagnetic resonance (EPR) and/or NMR imaging should satisfy the following two conditions: 1) the molecules disperse into tissues rapidly, and 2) paramagnetic loss occurs by simple reduction of the radical. T