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Pharmacokinetic Analysis of a New Slow-Release Preparation of Valproic Acid (KW6066N)

✍ Scribed by Toshiaki Kugoh; Hiroko Tanaka; Kiyoshi Hosokawa; Isamu Matsumoto


Book ID
118708390
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
130 KB
Volume
43
Category
Article
ISSN
1323-1316

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A new sustained release dosage form of valproic acid (VPA) was developed. The new sustained release dosage form was administered (twice, with and without food) to five dogs in comparison to a standard tablet (Depakine, Labaz) and an i.v. preparation of the drug. Drug level monitoring in the plasma w