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Pharmacogenetics of Tardive Dyskinesia: Combined Analysis of 780 Patients Supports Association with Dopamine D3 Receptor Gene Ser9Gly Polymorphism

✍ Scribed by Bernard Lerer; Ronnen H. Segman; Heiner Fangerau; Ann K. Daly; Vincenzo S. Basile; Roberto Cavallaro; Harald N. Aschauer; Robin G. McCreadie; Stephanie Ohlraun; Nicol Ferrier; Mario Masellis; Massimiliano Verga; Joachim Scharfetter; Marcella Rietschel; Roger Lovlie; Uriel Heresco Levy; Herbert Y. Meltzer; James L. Kennedy; Vidar M. Steen; Fabio Macciardi

Book ID
114280995
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
179 KB
Volume
27
Category
Article
ISSN
1470-634X

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Dopamine D3 receptor (DRD3) was demonstrated to have important implications in schizophrenia, because it binds antipsychotic drugs and is abundant in the limbic system of the brain. Several groups attempted to find an association between a serine-to-glycine polymorphism at codon 9 of the DRD3 gene (