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Pharmacogenetics of drug-induced birth defects: what is known so far?

โœ Scribed by Wilffert, Bob; Altena, Judith; Tijink, Laurien; van Gelder, Marleen MHJ; de Jong-van den Berg, Lolkje TW


Book ID
125499574
Publisher
Future Medicine
Year
2011
Tongue
English
Weight
866 KB
Volume
12
Category
Article
ISSN
1462-2416

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## Abstract ## BACKGROUND: Acetaminophen (APAP) use in early pregnancy has been associated with the risk of gastroschisis, a rare but serious congenital defect of the abdominal wall. The purpose of this study was to characterize the variability of APAP sulfation in a panel of human fetal livers an