A pharmacologic strategy for the treatme
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Stephen L. Dewey; Jonathan D. Brodie; Madina Gerasimov; Bryan Horan; Eliot L. Ga
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Article
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1999
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John Wiley and Sons
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English
โ 115 KB
๐ 3 views
Like many psychostimulant drugs, nicotine elevates extracellular and synaptic dopamine (DA) concentrations in the nucleus accumbens (NAc). This elevation has been linked to its reinforcing properties. Dopaminergic transmission within the NAc is modulated by gamma-aminobutyric acid (GABA). Therefore,