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Pharmacodynamics of cisplatin in human head and neck cancer: correlation between platinum content, DNA adduct levels and drug sensitivity in vitro and in vivo

โœ Scribed by Welters, M J P; Fichtinger-Schepman, A M J; Baan, R A; Jacobs-Bergmans, A J; Kegel, A; van der Vijgh, W J F; Braakhuis, B J M


Book ID
110000884
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
83 KB
Volume
79
Category
Article
ISSN
0007-0920

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โœ Marij J.P. Welters; Anne Marie J. Fichtinger-Schepman; Robert A. Baan; Mario A.J ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 91 KB ๐Ÿ‘ 2 views

Patients with head and neck squamous cell carcinoma (HNSCC) treated with cisplatin show a large inter-individual variation in tumor response. Little is known about factors that contribute to this variation. The aim of our study was to correlate the sensitivity to cisplatin with a number of cellular