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Pharmacodynamic Modeling of Thrombopoietin, Platelet, and Megakaryocyte Dynamics in Patients with Acute Myeloid Leukemia Undergoing Dose Intensive Chemotherapy

✍ Scribed by Bernstein, Steven H.; Jusko, William J.; Krzyzanski, Wojciech; Nichol, Janet; Wetzler, Meir

Book ID: 120992988
Publisher: Sage Publications
Year: 2002
Tongue: English
Weight: 260 KB
Volume: 42
Category: Article
ISSN: 0091-2700
DOI: 10.1177/00912700222011553

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## Abstract ## BACKGROUND Elderly patients (age ≥ 65 years) with acute myeloid leukemia (AML) generally have a poor prognosis. AML‐type therapy results are often derived from studies in younger patients and may not apply to elderly AML. Many investigators and oncologists advocate, at times, only s