Microbial kinetics of Escherichia coli NIHJ JC-2 and E. coli B/r were investigated in the presence of beta-lactam antibiotics. To maintain a constant drug concentration during the experiment, a novel technique, using a dialysis membrane tube containing the drug solution, was successfully employed. T
✦ LIBER ✦
Pharmacodynamic modeling of bacterial kinetics: β-Lactam antibiotics against Escherichia coli
✍ Scribed by Ronald C. Li; David E. Nix; Jerome J. Schentag
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 637 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0022-3549
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## Abstract The effects of three beta‐lactam antibiotics on __Escherichia coli__ were studied by means of flow cytometry. Since these agents block bacterial cell wall synthesis in such manner as to prevent septal formation without appreciably affecting nucleic acid synthesis, the resulting cell elo