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Pharmacodynamic enhancement of the anti-platelet antibody Fab abciximab by site-specific pegylation

โœ Scribed by Knight, David M.; Jordan, Robert E.; Kruszynski, Marian; Tam, Susan H.; Giles-Komar, Jill; Treacy, George; Heavner, George A.


Book ID
121430484
Publisher
Informa plc
Year
2004
Tongue
English
Weight
648 KB
Volume
15
Category
Article
ISSN
0953-7104

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Specific labeling is required for energy transfer measurements and to avoid artifacts in the use of fluorophores as reporter groups. Therefore, a method for specific modification by one of the most popular reagents for P-type ATPases (fluorescein 5-isothiocyanate) has been developed. Sulfhydryl reag