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Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice

โœ Scribed by Katrin M. Kirschbaum; Stefanie Henken; Christoph Hiemke; Ulrich Schmitt


Book ID
116284858
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
382 KB
Volume
188
Category
Article
ISSN
0166-4328

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โœ Wen-Ho Chang; Shu-Swei Jaw; Ho-Sheng Wu; Lacan Tsay; Eng-Kung Yeh ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 322 KB

Striatal homovanillic acid (HVA) levels and drug concentrations in striatum and plasma were examined in guinea pigs after acute and subchronic administrations of haloperidol (HAL) and reduced HAL (RHAL). HVA and drug levels were measured by high performance liquid chromatography with electrochemical