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Pharmacodynamic assay of thymidylate synthase activity in peripheral blood mononuclear cells

✍ Scribed by Dick Pluim, Kim A. A. Schilders…

Book ID
120752202
Publisher
Springer
Year
2013
Tongue
English
Weight
237 KB
Volume
405
Category
Article
ISSN
1618-2650

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✍ E.S.J. Arner; S. Eriksson 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 301 KB

Resting and stimulated human peripheral blood lymphocytes and monocyte-derived macrophages were incubated with tritiated deoxycytidine labeled at the 5position. Release of tritiated water into the medium was thereupon detected utilizing its lack of binding to active charcoal, which is an established