Pharmaceutically active secondary metabolites of microorganisms
β Scribed by A. L. Demain
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 103 KB
- Volume
- 52
- Category
- Article
- ISSN
- 1432-0614
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Plants provide a rich source of novel biologically active compounds. Biological and chemical screenings are complementary approaches for the rapid detection and isolation of interesting new plant constituents. Biological screening followed by activity-guided fractionation has been used successfully
Eight secondary metabolites, two isolated from Zieria smithii and six from Zanthoxylum elephantiasis were investigated for their biological (antimicrobial and cytotoxic) activities against 15 pathogenic microorganisms and on brine shrimps. Canthine-6-one obtained from Z. elephantiasis was shown to h