PHARMACEUTICAL CRYSTALS : science and en
β LI, TONGLEI. MATTEI ALESSANDRA
π Library
π
2018
π WILEY-BLACKWELL
π English
β¦ LIBER β¦
π
Pharmaceutical salts and co-crystals
β Scribed by Johan Wouters; Luc QueΜreΜ;
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Leaves
- 407
- Series
- RSC drug discovery series, 16
- Category
- Library
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No coin nor oath required. For personal study only.
β¦ Synopsis
Multi-component crystalline materials (salts and co-crystals) have received renewed interest due to their importance in the pharmaceutical industry, and pharmaceutical co-crystals and salts represent an emerging class of pharmaceutical materials offering the prospect of optimized physical properties, giving new, stable and patentable solid forms. These multi-component crystalline forms influence relevant physico-chemical parameters such as solubility, dissolution rate, chemical stability, melting point, and hygroscopicity, which can result in solids with properties superior to those of the free drug. This book covers the hot topic of pharmaceutical salts and co-crystals focusing on the following essential aspects an overview of fundamental aspects on salts and co-crystals, racemic resolution via diastereomer separation, optimization of relevant physico-chemical parameters and strengthening of intellectual property. Combining both reports of the latest research and comprehensive overviews of basic principles, with contributions from selected experts in both academia and industry, this unique book is an essential reference, ideal for pharmaceutical development scientists and graduate students in pharmaceutical science. Read more... Content: Fundamental Aspects on Salts and Co-crystals; Preparative Methods for Co-crystals; Characterization of Co-crystals and Salts; Applications of Co-crystals and Salts in Pharmaceutical Solid State Property Management Abstract: This unique book focuses on the currently 'hot topic' of Pharmaceutical Salts and Co-crystals. Combining both reports of the latest academic research and comprehensive overviews of basic principles, with more applied contributions from selected experts in industry. Read more...
β¦ Table of Contents
Pharmaceutical Salts and Cocrystals_Publicity......Page 1
i-iv......Page 2
v-vi......Page 6
vii-xiv......Page 8
1-8.pdf......Page 16
9-28......Page 24
29-43......Page 44
44-88......Page 59
89-109......Page 104
110-127......Page 125
128-153......Page 143
154-187......Page 169
188-211......Page 203
212-246......Page 227
247-279......Page 262
280-299......Page 295
300-317......Page 315
318-329......Page 333
330-337......Page 345
338-382......Page 353
383-392......Page 398
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