Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization
โ Scribed by Thorsteinn Loftsson; Marcus E. Brewster
- Book ID
- 109388521
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 303 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Phase-solubility diagrams are frequently used to calculate stoichiometry of drug/cyclodextrin complexes. Linear diagrams (A(L)-type systems) are thought to indicate that the complexes are first order with respect to cyclodextrin and first or higher order with respect to the drug. Positive deviation
The objective of this mini-review is to summarize the findings concerning the properties and the pharmaceutical applications of multicomponent complexes made of a sparingly water-soluble amino-type drug, a cyclodextrin, and a hydroxy carboxylic acid. Simultaneous complexation and salt formation with