Phalangeal Lytic Lesions in Multiple Myeloma
β Scribed by Capalbo, Silvana; Mascolo, Vito
- Book ID
- 118629174
- Publisher
- CIG Media Group, LP.
- Year
- 2007
- Tongue
- English
- Weight
- 357 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1557-9190
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Osteopontin (OPN), a secreted phosphoprotein involved in immune regulation and bone homeostasis, is a major component of bone, the natural habitat of longβlived plasma cells and multiple myeloma (MM). We show that only some MM cell lines and primary patient samples express OPN at high l
This study was conducted to determine whether individual bony lesions are specific for recognizing multiple myeloma and thereby distinguish it from metastatic cancer and leukemia. The lytic skeletal lesions of multiple myeloma are characterized by sharply defined, spheroid lesions. They have smooth