Phagocytosis of rod outer segments by human iris pigment epithelial cells in vitro
β Scribed by G. Thumann; Karl Ulrich Bartz-Schmidt; Klaus Heimann; Ulrich Schraermeyer
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 617 KB
- Volume
- 236
- Category
- Article
- ISSN
- 0065-6100
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π SIMILAR VOLUMES
Retinal pigment epithelium (RPE) cells in culture display selective induction of certain early response transcription factors at the onset of photoreceptor rod outer segment (ROS)-specific phagocytosis (Ershov et al., 1996a). Moreover, this response is modulated by prostaglandins. The purpose of thi
Cultured normal rat retinal pigment epithelium (PE) ingested six times more rod outer segments in the presence of 20% fetal bovine serum than in serumfree medium. PE cultured from Royal College of Surgeons (RCS) rats with hereditary retinal dystrophy, known to have a defect in vivo in the phagocytos
## Abstract The retinal pigment epithelium is uniquely suited to gene therapy that uses lipidβmediated DNA transfer due to its high phagocytic activity in situ. We compared the relative efficacy of phagocytosis on the uptake of labeled plasmid vectors by retinal pigment epithelial and ciliary epith