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Phagocytosis of bacterial aggregates by granulocytes

✍ Scribed by F. Galdiero; C. Romano Carratelli; I. Nuzzo; C. Bentivoglio; M. Galdiero

Publisher
Springer
Year
1988
Tongue
English
Weight
423 KB
Volume
4
Category
Article
ISSN
0393-2990

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✦ Synopsis

A study was conducted on the granulocytic phagocytosis of bacterial aggregates obtained under ideal environmental conditions. For the strains studied, aggregation was favored by low salt concentrations, low pH and temperatures between 30Β°C and 40Β°C. Our results show that the phagocytic capacity of granulocytes depends on the type and size of these aggregates. Those formed by a smaller number of cells are more easily phagocytized than the larger ones.

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## Abstract The internalization of membrane markers during phagocytosis was followed in guinea pig granulocytes as a function of the extent of particle ingestion. The plasmalemma was carefully labeled with diazotized ^35^S‐sulfanilate, or by treatment with periodate and sodium ^3^H‐borohydride. The