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Phagocytosis of Apoptotic Neutrophils Regulates Granulopoiesis via IL-23 and IL-17

✍ Scribed by Matthew A. Stark; Yuqing Huo; Tracy L. Burcin; Margaret A. Morris; Timothy S. Olson; Klaus Ley


Book ID
116570410
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
486 KB
Volume
22
Category
Article
ISSN
1074-7613

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## Abstract IL‐23 plays a critical role in the expansion of highly proinflammatory Th17 cells secreting IL‐17 and IL‐22. Recently, we demonstrated that Notch signaling drives IL‐22 secretion through the aryl hydrocarbon receptor (AHR) and plays a protective role in Con A‐induced hepatitis. In this