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Phagocytosis of Apoptotic Bodies by Hepatic Stellate Cells Occurs in Vivo and Is an Important Mechanism in Liver Fibrogenesis

✍ Scribed by Natalie Torok; Jian Wu; Mark Zern; Charles Halsted; Samuel French; Scott Friedman; Shan–Shan Zhan


Book ID
119758765
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
36 KB
Volume
129
Category
Article
ISSN
0016-5085

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Phagocytosis of apoptotic bodies by hepa
✍ Shan-Shan Zhan; Joy X. Jiang; Jian Wu; Charles Halsted; Scott L. Friedman; Mark 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 923 KB

Hepatic stellate cell activation is a main feature of liver fibrogenesis. We have previously shown that phagocytosis of apoptotic bodies by stellate cells induces procollagen ␣1 (I) and transforming growth factor beta (TGF-␤) expression in vitro. Here we have further investigated the downstream effe