𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Phage idiotype vaccination: first phase I/II clinical trial in patients with multiple myeloma

✍ Scribed by Roehnisch, Tim; Then, Cornelia; Nagel, Wolfgang; Blumenthal, Christina; Braciak, Todd; Donzeau, Mariel; Böhm, Thomas; Flaig, Michael; Bourquin, Carole; Oduncu, Fuat S


Book ID
125401159
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
459 KB
Volume
12
Category
Article
ISSN
1479-5876

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Phase II trial of amsacrine in patients
✍ Greipp, Philip R. ;Coleman, Morton ;Anderson, Keaven ;McIntyre, O. Ross 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB

Seventy-four previously treated patients with multiple myeloma were treated with Amsacrine (m-AMSA) 120 mg/m2 every 3 weeks. A good response was observed in two patients (3%), and improvement was seen in three patients (4%). Severe toxicity was observed in 33% of patients who received three or more

A Phase I–II trial of polyethylene glyco
✍ Neeraj R. Agrawal; Ronald M. Bukowski; Lisa A. Rybicki; Joanne Kurtzberg; Lewis 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 77 KB

## Abstract ## BACKGROUND Multiple myeloma remains an incurable disease. New agents are needed to improve therapy for patients with this disease. Previous investigators evaluated in vitro sensitivity of myeloma cells to polyethylene glycol‐conjugated L‐asparaginase (PEG‐L‐asparaginase) using the h

Phase II trial of temsirolimus in patien
✍ Sherif S. Farag; Shuhong Zhang; Buffy S. Jansak; Xiaojing Wang; Eric Kraut; Kenn 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 508 KB

In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat

Interferon alfa-2b/melphalan/prednisone
✍ M. Robert Cooper; Alexander Fefer; John Thompson; Delvyn C. Case; Raymond Kempf; 📂 Article 📅 1987 🏛 Springer US 🌐 English ⚖ 419 KB

Interferon alfa-2b (Intron A; Schering Plough) has been shown to be active in advanced previously treated multiple myeloma (MM). Recent in vitro evidence has suggested synergy between cytotoxic agents and interferon alfa-2b. This phase I-II protocol was initiated to study interferon alfa-2b in combi