pH-sensitive swelling and release behaviors of anionic hydrogels for intelligent drug delivery system
β Scribed by Bumsang Kim; Youngchan Shin
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 128 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0021-8995
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π SIMILAR VOLUMES
A temperature-and pH-responsive drug delivery system was studied by using interpenetrating polymer network (IPN) hydrogels constructed with poly(acrylic acid) (PAAc) and poly(vinyl alcohol) (PVA). The release of indomethacin incorporated into these hydrogels showed pulsatile patterns in response to
## Abstract Biodegradable poly(aspartic acid) (PASP) hydrogel and PASP/gelatin complex were prepared to evaluate their potential application as pHβsensitive matrices for controlled protein release. Entrapment of myoglobin (Mb) and its release were compared between the two types of carriers. It was