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pH-Sensitive polymers that enhance intracellular drug delivery in vivo

✍ Scribed by Themis R Kyriakides; Charles Y Cheung; Niren Murthy; Paul Bornstein; Patrick S Stayton; Allan S Hoffman


Book ID
114161434
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
953 KB
Volume
78
Category
Article
ISSN
0168-3659

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Gastrointestinal performance of tablets coated with pH responsive acrylic polymers (Eudragit) was investigated in human volunteers. Tablet cores were coated with Eudragit S dissolved in ethanol (organic), Eudragit S aqueous dispersion (aqueous), or Eudragit FS aqueous dispersion. Eight fasted volunt