✦ LIBER ✦

pH-Sensitive Chitosan/Gelatin Hybrid Polymer Network Microspheres for Delivery of Cimetidine

✍ Scribed by De Yao, Kang; Xu, Mei Xuan; Yin, Yu Ji; Zhao, Jin Ying; Chen, Xiu Lan

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 935 KB
Volume: 39
Category: Article
ISSN: 0959-8103
DOI: 10.1002/(sici)1097-0126(199604)39:4<333::aid-pi502>3.0.co;2-c

No coin nor oath required. For personal study only.

✦ Synopsis

pH responsive chitosan/gelatin hybrid polymer network (HPN) microspheres were prepared via the inverse emulsion crosslinking method. Cimetidine release from the microspheres was studied. The drug only delivers in acidic medium, while the release rate can be controlled by the HPN composition and the degree of deacetylation.

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