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pH-Induced insertion of the amphiphilic α-helical anchor of Escherichia coli penicillin-binding protein 5

✍ Scribed by David A. PHOENIX; Julie M. PRATT

Book ID: 115127901
Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 497 KB
Volume: 190
Category: Article
ISSN: 1432-1327
DOI: 10.1111/j.1432-1033.1990.tb15584.x

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## Abstract Penicillin‐binding protein 5 (PBP5) is a DD‐carboxypeptidase, which cleaves the terminal D‐alanine from the muramyl pentapeptide in the peptidoglycan layer of __Escherichia coli__ and other bacteria. In doing so, it varies the substrates for transpeptidation and plays a key role in main