pH-dependent helix folding dynamics of poly-glutamic acid
โ Scribed by Gooding, Edward A.; Sharma, Sapna; Petty, Sarah A.; Fouts, Elizabeth A.; Palmer, Colin J.; Nolan, Brian E.; Volk, Martin
- Book ID
- 123269096
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 480 KB
- Volume
- 422
- Category
- Article
- ISSN
- 0301-0104
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๐ SIMILAR VOLUMES
## Abstract The equilibrium structural ensemble of a 20โresidue polyglutamic acid peptide (E~20~) was studied with FRET, circular dichroism, and molecular dynamics (MD) simulations. A FRET donor, __o__โaminobenzamide, and acceptor, 3โnitrotyrosine, were introduced at the Nโ and Cโtermini, respectiv
The folding of randomly coiled poly(bg1utamic acid) to the helical state has been studied in N-methylacetamide by titration methods. Since this solvent would be expected to form amide-peptide group hydrogen bonds with the unfolded form of the polymer, to a first approximation no helix stabilization