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pH-Dependent exposure of endoproteolytic cleavage sites of the adenovirus 2 hexon protein

✍ Scribed by Einar Everitt; Mikael J. Persson; Claes Wohlfart

Book ID
109314293
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
371 KB
Volume
49
Category
Article
ISSN
0378-1097

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The quality and stability of recombinant adenovirus preparations for gene therapy trials are currently analyzed by anion-exchange HPLC. It was shown that the retention time of the adenovirus peak increased over the course of time upon storage in current liquid formulations. The number of isoaspartat