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pH Dependence of Stability of the 10th Human Fibronectin Type III Domain: A Computational Study

✍ Scribed by Buddhadeb Mallik; Li Zhang; Shohei Koide; Dimitrios Morikis

Book ID: 109387626
Publisher: American Institute of Chemical Engineers
Year: 2008
Tongue: English
Weight: 320 KB
Volume: 24
Category: Article
ISSN: 8756-7938
DOI: 10.1021/bp0700915

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## Abstract Although it is well documented that proteins adsorb onto biomaterial surfaces, relatively little is quantitatively understood about the effects of adsorption on protein orientation and conformation. Because this is the primary determining factor of protein bioactivity, the ability to ac