PGI2 The Relationship Between Acute and Chronic Acetaminophen Exposure and Liver Toxicity
โ Scribed by M.N. Gokhale; H.R. Foster; M. Cleves; W.R. Hogan; L.P. James; B. Martin
- Book ID
- 119310710
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 69 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1098-3015
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๐ SIMILAR VOLUMES
Liver transplantation (LT) may be life-saving in severe acute liver failure (ALF). The aim of this study was to compare the utilization of LT in acetaminophen and non-acetaminophen ALF. Between 1992 and 2006, 469 patients with ALF were admitted, and 104 underwent LT. Acetaminophen was the most commo
Despite extensive investigations, the cause of liver injury in 14% of patients with acute liver failure remains unknown (indeterminate). In a pilot study using a novel assay, highly specific acetaminophen-cysteine adducts were detected in 7 of 36 indeterminate patients (19%). To extend these observa