Mapping of a translocation breakpoint in
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Nicholas Hearle; Anneke Lucassen; Rubin Wang; Wendy Lim; Fiona Ross; Robert Whee
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Article
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2004
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John Wiley and Sons
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English
β 279 KB
π 1 views
## Abstract Germβline mutations in the serineβthreonine kinase gene __STK11__ (__LKB1__) cause PeutzβJeghers syndrome (PJS), a rare autosomal dominantly inherited disease, characterized by hamartomatous polyposis and mucocutaneous pigmentation. __STK11__ mutations only account for about half of PJS