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PET imaging of HER1-expressing xenografts in mice with86Y-CHX-A″-DTPA-cetuximab

✍ Scribed by Tapan K. Nayak; Celeste A. S. Regino; Karen J. Wong; Diane E. Milenic; Kayhan Garmestani; Kwamena E. Baidoo; Lawrence P. Szajek; Martin W. Brechbiel

Publisher
Springer
Year
2010
Tongue
English
Weight
360 KB
Volume
37
Category
Article
ISSN
0340-6997

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✍ Tapan K. Nayak; Kayhan Garmestani; Kwamena E. Baidoo; Diane E. Milenic; Martin W 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 407 KB

## Abstract Bevacizumab is a humanized monoclonal antibody that binds to tumor‐secreted vascular endothelial growth factor (VEGF)‐A and inhibits tumor angiogenesis. In 2004, the antibody was approved by the US Food and Drug Administration (FDA) for the treatment of metastatic colorectal carcinoma i