Nasal inoculation of an adenovirus vecto
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Hong-Duck Kim; Kazuki Tahara; J. Adam Maxwell; Robert Lalonde; Tatsuya Fukuiwa;
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Article
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2007
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John Wiley and Sons
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English
⚖ 394 KB
Background One of the pathological hallmarks of Alzheimer's disease (AD) is deposits of amyloid β-peptide (Aβ) in neuritic plaques and cerebral vessels. Immunization of AD mouse models with Aβ reduces Aβ deposits and improves memory and learning deficits. Because recent clinical trials of immunizati