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PET and tissue autoradiography evidence of decline of metabotropic glutamate receptor type 5 (mGluR5) in the prefrontal cortex of Alzheimer's disease

โœ Scribed by Pedro Rosa-Neto; Serge Gauthier; Jean-Paul Soucy; Jared Rowley; Sara Mohades; Dorothee Schoemaker; Luciano Minuzzi


Book ID
118467149
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
190 KB
Volume
7
Category
Article
ISSN
1552-5260

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The cellular and subcellular localization of the mGluR5 metabotropic glutamate receptor subtype was studied in the rat cerebellar cortex, by using the preembedding immunoperoxidase and immunogold techniques. Light microscopic observations revealed an abundant, intense labeling of neurons in the gra