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Pertussis infection and vaccination induces Th1 cells

✍ Scribed by Miriam T. Brady; Bernard P. Mahon; Kingston H.G. Mills

Book ID: 104298996
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 90 KB
Volume: 19
Category: Article
ISSN: 0167-5699
DOI: 10.1016/s0167-5699(98)01359-0

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## Abstract Pertussis toxin (PTX) is an ancillary adjuvant used to elicit experimental allergic encephalomyelitis (EAE), the principal autoimmune model of multiple sclerosis. One mechanism whereby PTX potentiates EAE is to increase blood–brain barrier (BBB) permeability. To elucidate further the me