Thiol-based redox reactions are involved in the regulation of a variety of biological functions, such as protection against oxidative stress, signal transduction and protein folding. Some proteins involved in redox regulation have been shown to modulate life span in organisms from yeast to mammals.
✦ LIBER ✦
Perspectives on the mitochondrial etiology of replicative aging in yeast
✍ Scribed by Ana Ugidos; Thomas Nyström; Antonio Caballero
- Book ID
- 113615358
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 162 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0531-5565
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## Abstract Mitochondrial DNA (mtDNA) mutations escalate with increasing age in higher organisms. However, it has so far been difficult to experimentally determine whether mtDNA mutation merely correlates with age or directly limits lifespan. A recent study shows that budding yeast can also lose fu
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