Perspectives on the ARE as it turns 25 y
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Daniel Beisang; Paul R. Bohjanen
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Article
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2012
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Wiley (John Wiley & Sons)
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English
β 476 KB
## Abstract The AUβrich element (ARE) was discovered in 1986 as a conserved mRNA sequence found in the 3β² untranslated region of the TNFβ__Ξ±__ transcript and other transcripts encoding cytokines and inflammatory mediators. Shortly thereafter, the ARE was shown to function as a regulator of mRNA deg