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Perspectives on Neonatal Hypoxia/Ischemia-Induced Edema Formation

✍ Scribed by Diana Carolina Ferrari; Olivera Nesic; Jose Regino Perez-Polo

Publisher
Springer
Year
2010
Tongue
English
Weight
369 KB
Volume
35
Category
Article
ISSN
0364-3190

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## Abstract Neonatal hypoxia/ischemia (HI) is a common cause of cognitive and behavioral deficits in children with hyperoxia treatment (HHI) being the current therapy for newborn resuscitation. HI induces cerebral edema that is associated with poor neurological outcomes. Our objective was to charac

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## Abstract Aquaporin‐4 (AQP4), a water channel protein, is abundantly expressed in astrocytes and plays a key role in the development of brain edema. However, it is not clear whether AQP4 contributes to astrocytic swelling in hypoxia–ischemia (HI). To investigate the roles of AQP4 in astrocytic sw