Medicinal chemistry: Past, present and f
β
W. So
π
Article
π
2010
π
Elsevier Science
π
English
β 678 KB
## Abstract Drug discovery in the past and, to a lesser extent, at present has been (is) based on molecular manipulation of natural products. In this way, selective local anesthetics have been developed from cocaine From atropine via pethidine, potent morphinomimetics, antiβtussives, antiβdiarrhea