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Persistent rubella-specific IgM reactivity in the absence of recent primary rubella and rubella reinfection

✍ Scribed by H. I. J. Thomas; Dr. P. Morgan-Capner; A. Roberts; L. Hesketh

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
425 KB
Volume
36
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

Between two and seven sera from cases of persistent detection of rubella‐specific IgM for periods in excess of 2.5 months, but in the absence of recent primary rubella or rubella reinfection, were examined for rheumatoid factor, heterophile antibody, and IgM reactivity against toxo‐plasma and a number of viruses. The relative avidity of the rubella‐specific lgG, has been assessed in all the sera by two methods.

None of the sera contained rheumatoid factor or heterophile antibody, nor did any contain detectable concentrations of IgM specific for any of the panel of antigens apart from five sera which contained low concentrations of IgM specific for some coxsackieviruses B. No sera were positive for low avidity specific IgG, although three did give equivocal results with one avidity test and one gave equivocal results with the second avidity test.

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