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Persistent infiltration of CD45RC−CD4+ T cells, Th2-like effector cells, in prolonging hepatic allografts in rats pretreated with a donor-specific blood transfusion

✍ Scribed by N Miyanari; Y Yamaguchi; K Matsuno; A Tominaga; M Goto; O Ichiguchi; K Mori; M Ogawa


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
426 KB
Volume
25
Category
Article
ISSN
0270-9139

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✦ Synopsis


Methods

remains unclear. 1 Clonal deletion, 2 suppressor T cells, 3 veto Animals. Inbred male Lewis (LEW) (RT1 1 ) and ACI(RT1 a ) rats bred at the Kumamoto University Animal Research Center (Kumamoto, Japan) were used as transplant recipients and donors, respec-Abbreviations: DST, donor-specific blood transfusion; IL, interleukin; Th, T-helper cells; LEW, Lewis; FACS, flourescence-activated cell sorter; RT-PCR, reverse-transcriptase poly-tively. These rat strains originated at the Central Institute for Expermerase chain reaction; IFN-g, interferon gamma.