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Persistent gene expression in rat liver in vivo by repetitive transfections using HVJ-liposome

✍ Scribed by Hirano, T; Fujimoto, J; Ueki, T; Yamamoto, H; Iwasaki, T; Morisita, R; Sawa, Y; Kaneda, Y; Takahashi, H; Okamoto, E

Book ID
110038177
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
596 KB
Volume
5
Category
Article
ISSN
0969-7128

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The lack of a small animal model of hepatitis C virus (HCV) infection has impeded elucidation of the pathogenesis of HCV. The aim of this study was to develop an HCV-expressing animal model by means of cationic liposome-mediated in uiuo gene transfer. To examine the feasibility of this strategy, pAc