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Persistent expression of Pax3 in neural crest causes cleft palate and defective osteogenesis

✍ Scribed by Meilin Wu; Jun Li; Kurt A. Engleka; Bo Zhou; MinMin Lu; Joshua Plotkin; Jonathan A. Epstein

Book ID: 116976789
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 78 KB
Volume: 319
Category: Article
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2008.05.120

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## Abstract The developmental gene __PAX 3__ is expressed in the early embryo in developing muscle and elements of the nervous system, including the brain. Since no one has investigated the expression of the isoforms of __PAX 3__ in the neuroectodermal tumors melanoma and small cell lung cancer (SC